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Changes in resistance among coliform bacteraemia associated with a primary care antimicrobial stewardship intervention: A population-based interrupted time series study.

PLoS Med · 2019 · PMC6555503 · PMID 31173597

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Differences between observed and predicted co-amoxiclav resistance were in the direction of a reduction, consistent with flattening of a previously rising trend, but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.