MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway.

Liver metastatic tumours showed a trend toward higher miR-338-5p/PIK3C3 ratio than primary tumours in the spleen, although no statistical significance was reached ( P = 0.6905, Mann-Whitney test) ( Fig. 3 g).

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