Impaired Fear Extinction Recall in Serotonin Transporter Knockout Rats Is Transiently Alleviated during Adolescence.

Brain Sci · 2019 · PMC6562656 · PMID 31121975

Europe PMC DOI

hedged sentences

0.0860

closest p · 1.7× alpha

0.0860

boldest claim

The sentences

showed a trendp = 0.086so close (0.05 < p ≤ 0.1)

mPFC BDNF expression following extinction was also dependent on age (F (2,39) = 7.507, p = 0.002) and showed a trend towards an effect of genotype (F (1,39) = 3.107, p = 0.086), without displaying a genotype × age interaction (F (2,39) = 1.185, p = 0.316).

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failed to reach significanceno p-value reported

Whereas augmented fear extinction learning seems to be responsible for the improved fear extinction recall observed in 5-HTT −/− rats during adolescence, age × genotype effects on learning rates failed to reach significance.

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