Renal Regenerative Potential of Extracellular Vesicles Derived from miRNA-Engineered Mesenchymal Stromal Cells.

mTECs treated with miR-10a-5p (miR10a), miR-127-3p (miR127), miR-29a-3p (miR29a) and miR-486-5p (miR486) were able to proliferate to some degree in the hypoxia/reoxygenation culture, even if the obtained results did not reach statistical significance, unlike let-7b- and miR-30a-5p- (miR30a-)treated tubular cells ( Figure 1 ), which only supported the beneficial effects of selected EV-miRNAs in AKI. 2.2.

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