Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague⁻Dawley Rats ^†.

HepG2 cells that received the conditioned medium from macrophages that were treated with CTD-002 showed a trend towards reduced TNFα secretion ( Figure 2 A).

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In addition, incubating hepatic HepG2 cells with the conditioned medium derived from CTD-002-treated BMDMs showed a decreasing trend in inflammation compared to control cells.

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