Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade.

Nat Commun · 2019 · PMC6584502 · PMID 31217437

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The remaining genes, uniquely upregulated in the combination group, also showed a trend toward induction in mice receiving anti-PD1 only (Fig. 4c ), and even the common DEG were more significantly upregulated in the combination group.

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