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Genomic Variation and Pharmacokinetics in Old Age: A Quantitative Review of Age- vs. Genotype-Related Differences.

Clin Pharmacol Ther · 2019 · PMC6585622 · PMID 29498032

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showed a trendno p-value reported
The presented meta‐analysis of PK variation showed a trend towards higher variation in the elderly, but that was not ubiquitous and not so excessive that it could eliminate the genotype effects in old age.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.