Thus, we next investigated adhesion of MSCs to titanium and showed that while the highest concentration of PI3K inhibitors (10 μM) reduced adhesion, this effect did not reach statistical significance, in accordance with the lesser PI3K activation in response to titanium engagement of MSCs (Figure 5 e).
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Human mesenchymal stromal cells in adhesion to cell-derived extracellular matrix and titanium: Comparative kinome profile analysis.
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