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Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain.

Front Pharmacol · 2019 · PMC6586922 · PMID 31258480

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showed a trendno p-value reported
In contrast, U50,488 did not significantly reduce respiration at any time point (and, in fact, showed a trend toward increased respiration).

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