In addition to decreased T lymphocyte levels, there were reductions in peripheral blood and pulmonary B lymphocytes in hSTING - N154S mice, although in the lungs, this did not reach statistical significance.
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Expression of a constitutively active human <i>STING</i> mutant in hematopoietic cells produces an <i>Ifnar1</i>-dependent vasculopathy in mice.
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