However, at the level of its mRNA, the prognostic analysis of METTL3 from tumor samples with detailed clinical information which were downloaded from TCGA database showed a trend of adverse prognosis in both METTL3 and bladder cancer, but it had no statistical significance (Additional file 3 : Figure S1b).
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METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner.
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