Divergent Metabolic Effects of Acute Versus Chronic Repeated Forced Swim Stress in the Rat.

Impact of chronic repeated FS stress and acute FS stress on body weight gain, caloric intake, and caloric efficiency, measured up until 4 days after stress As was the case in experiment 1, rats exposed to chronic FS stress gained less weight and showed reduced caloric efficiency during the stress period than the controls (experiment 2; Figure 4 A: Wald χ 2 1 = 7.34; P < 0.01; Figure 4 E: Wald χ 2 1 = 6.52; P < 0.05), although in this experiment, the reduction in food intake did not reach statistical significance (Figure 4 C).

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