Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination.

Immunity · 2019 · PMC6591005 · PMID 31216462

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did not reach statistical significanceno p-value reported

Although emergent antibodies (7.1 ± 0.5% mean rate of somatic hypermutation) were slightly less mutated than the pre-existing antibodies (8.2 ± 1.1%), this difference did not reach statistical significance.

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