Cardiovascular, electrophysiologic, and hematologic effects of omega-3 fatty acids beyond reducing hypertriglyceridemia: as it pertains to the recently published REDUCE-IT trial.

found no benefit, a 10% decrease in cardiovascular outcomes with marginal significance was noted.

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mc yes pmc-license-ref CC BY issue-copyright-statement © The Author(s) 2019 Background The decline in coronary artery disease (CAD)-related mortality over the last four to five decades was regarded as a major breakthrough [ 1 ]; however, multiple rebutting reports from recent years that demonstrate an increasing trend towards higher mortality rates from CAD in specified patient populations exist [ 2 , 3 ].

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The secondary end points also did not reach statistical significance, which included POAF lasting for > 1 h, symptomatic AF, or AF requiring cardioversion [ 91 ].

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