The overall test for difference in adjusted mean 5‐ASA concentration (averaged over location) between the three 5‐ASA formulation groups (Table 2 ) did not reach statistical significance ( P = 0.099), but pairwise comparisons revealed a significant higher mean concentration in patients using Mezavant compared with Pentasa (geometric mean 2.39 ng/mg vs 0.57 ng/mg, P = 0.033) and a nonsignificant higher mean value compared to the Asacol group (2.39 ng/mg vs 1.60 ng/mg, P = 0.50).
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Mucosal 5-aminosalicylic acid concentration, drug formulation and mucosal microbiome in patients with quiescent ulcerative colitis.
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0.0990
0.0990