Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation.

Supervised clustering of transcripts representing either the PN, classical (CL), or MES subtype ( Table S1 ; Verhaak et al., 2010 ) across tumor regions showed a clear trend of accumulation of the MES signature in the perinecrotic and pseudopalisading tumor regions (central core) and a predominant PN signature at the invading edge (leading edge; Figure 1A ).

also in 19,460 other papers