Dengue Mosaic Vaccines Enhance Cellular Immunity and Expand the Breadth of Neutralizing Antibody Against All Four Serotypes of Dengue Viruses in Mice.

Front Immunol · 2019 · PMC6596366 · PMID 31281322

Europe PMC DOI

hedged sentence

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closest p · 1.6× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Although some comparisons did not reach statistical significance, e.g., pMos1 vs. pDen1 with DENV1 stimulation after the 1st dose ( p = 0.08), the mean PRNT values were dramatically elevated in the mice immunized with pMos1 compared with pDen1 immunized mice (386 vs. 84 with DENV1, 270 vs. 32 with DENV2, 172 vs. 32 with DENV3 and 60 vs. 14 with DENV4 stimulation).

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