Risk of Acute Liver Injury With Modern Antiretroviral Therapy

Compared to non-NRTI users, adjusted rates of liver aminotransferases >200 U/L were higher for initiators of a PI (HR, 1.39 [1.04–1.86]) or INSTI-based regimen (HR, 1.81 [0.77–4.22]), though the latter comparison did not reach statistical significance.

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