Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification.

B-cell depletion using an anti-CD20 antibody in a small cohort showed a trend in reducing inflammation, although nonsignificant 42 .

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We observed that those genes are highly significant, regardless of the data set used (Supplementary Fig. 8b ), and that 100% of them have the exact same expression trend, i.e., meaning that genes found upregulated in the microarray data set were also found upregulated in the RNA-seq data set, and vice versa (Supplementary Fig. 8c ).

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