Alcohol-induced IL-17A production in Paneth cells amplifies endoplasmic reticulum stress, apoptosis, and inflammasome-IL-18 activation in the proximal small intestine in mice.

Mucosal Immunol · 2019 · PMC6599481 · PMID 31105269

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showed a trendno p-value reported

Interestingly, in vivo administration of the IL-17A blocking antibody also showed a trend of reduction in the cleavage and activation of caspase-8, while control antibody had no effect ( Fig. 4E and F ).

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