Esculetin, a Coumarin Derivative, Prevents Thrombosis: Inhibitory Signaling on PLCγ2-PKC-AKT Activation in Human Platelets.

Int J Mol Sci · 2019 · PMC6600380 · PMID 31163690

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did not reach statistical significanceno p-value reported

The results suggested that esculetin slightly prolonged the bleeding time, but this finding did not reach statistical significance, showing that esculetin reduced platelet plug formation in vivo, without a significant change on prolonging the bleeding time.

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