Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue.

Hum Mol Genet · 2019 · PMC6602383 · PMID 31220268

Europe PMC DOI

hedged sentence

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closest p · 0.2× alpha

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boldest claim

The sentences

nominally significantP = 0.012actually significant

Although there was no evidence for differential ‘epigenetic aging’ in dup15q patients compared to controls in either cortical region (PFC: P = 0.06, TC: P = 0.45), there was a nominally significant association in CB ( P = 0.012) with dup15q carriers characterized by decelerated epigenetic aging compared to controls.

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