Although longer telomere length was associated with a higher risk of colon cancer, the result did not reach statistical significance (HR = 1.14, 95% CI: 0.88–1.48, P trend = 0.29, compared highest to the lowest quartile).
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Association Between Leukocyte Telomere Length and Colorectal Cancer Risk in the Singapore Chinese Health Study.
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Furthermore, only 1 study ( 19 ) reported separately the results for colon and rectal cancer; telomere length was higher in rectal cancer cases than controls, and the difference reached statistically borderline significance.