A randomized controlled trial to test efficacy and safety of thrombectomy in stroke with extended lesion and extended time window.

In 28 patients with ASPECTS 0–4 no treatment effect was evident with an OR of 1.1 (95% CI 0.1–8.4) for benefit in the thrombectomy group, while in 92 patients with ASPECTS 5–7 with an OR of 2.0 (0.9–4.4) a clear trend for a treatment benefit was observed. 1 In a meta-analysis of individual patient data from the five positive thrombectomy trials, no treatment effect was observed for patients with ASPECTS 0–5 with an OR of 1.24 (95% CI 0.62–2.49). 6 A recently published bicentric registry study which included 218

also in 19,460 other papers