Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis.

Front Psychiatry · 2019 · PMC6609575 · PMID 31316402

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a significant trendno p-value reported

Examination of regression residuals did not support the existence of a significant trend, however (data not shown).

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a slight trendno p-value reported

When studies were ranked from high glucocorticoid resistance in patients to low glucocorticoid resistance using the “glucocorticoid resistance index,” there was a slight trend for studies that reported high glucocorticoid resistance in patients to produce larger effect sizes (based on 170 patients and 187 controls; Figure 4A ).

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