Loss of function mutation of Eftud2, the gene responsible for mandibulofacial dysostosis with microcephaly (MFDM), leads to pre-implantation arrest in mouse.

PLoS One · 2019 · PMC6611600 · PMID 31276534

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did not reach statistical significanceno p-value reported

Although a slight reduction in Upf1 mRNA level was observed ( S2B Fig ), this decrease did not reach statistical significance.

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