The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells.

Subsequently, we observed a mean 28% decrease in total RPS6 abundance ( t test, control: 159.10 ± 48.52, overexpression: 108.8 ± 48.52, t 16 = 2.88, p = .011, p corrected = .044) and a highly significant 300% increase in RPS6 phosphorylation ( t test, control: 31.03 ± 10.66, overexpression: 124.10 ± 8.20, t 16 = 20.76, p < .001, p corrected < .001) ( Figure 3G ).

also in 132,142 other papers

There was also a nominally significant reduction in climbing success on knockdown of CG32549 using the ACT5C promoter (UAS = 90.6% ± 9.7%, UAS-KD = 77.7% ± 13.4%, t test: t 17 = 2.4, p = .029, n = 10 per condition on average, Bonferroni (adjusted for three comparisons) p > .05).

also in 7,732 other papers