Notch-mediated inhibition of neurogenesis is required for zebrafish spinal cord morphogenesis.

This raises the question whether the observed alteration in mib1 ta52b mutant neural tube proportions may be a secondary consequence of this reduction in cell number? Our observations argue against this hypothesis: First, the injection of NICD promotes a partial but clearly significant (p = 1.14E-08) restoration of neural tube proportions (Fig. 8p,q ) while triggering only a minor and non-significant (p = 0.129) increase in neural tube cell number (Supplementary Fig.

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