Anti-aging interventions affect lifespan variability in sex, strain, diet and drug dependent fashion.

When gender was taken into consideration and the studies were split according to effect of diet, genotype, or diet plus genotype, it was found that when mice had longevity extending genotypes and were treated with CR, variance of females increased near statistical significance (χ 2 = 3.25; df = 1; p = 0.071), while in males this seemed not the case ( Figure 3 ; Table 3 ).

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Moreover, distribution of the data suggested a possible trend for variance in female data changing in the opposite direction ( Fig 1 ).

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