Shared genes between Alzheimer's disease and ischemic stroke.

CNS Neurosci Ther · 2019 · PMC6630005 · PMID 30859738

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nominally significantno p-value reported

To reduce the possibility of a single disease driving the cross‐disease associations and uncover truly pleiotropic genes shared by AD and IS, we focused on shared genes that were nominally significant in each disease ( P AD < 0.05 and P IS < 0.05). 2.2.2 Meta‐analysis using Fisher's method We used Fisher's method to combine the P ‐values calculated by the VEGAS2 for each gene shared by AD and IS.

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