Dynamic Compressive Loading Improves Cartilage Repair in an In Vitro Model of Microfracture: Comparison of 2 Mechanical Loading Regimens on Simulated Microfracture Based on Fibrin Gel Scaffolds Encapsulating Connective Tissue Progenitor Cells.

Although the unloaded and compressively loaded constructs possessed greater relative GAG production at earlier time points (ie, days 7 and 14) compared with day 0, these differences did not reach statistical significance.

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Finally, we found a mild trend toward higher integration strength with the surrounding hyaline cartilage but no significant increase when compared with day 0 controls.

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