Pancreatic ductal cells may have a negative effect on human islet transplantation.

A subanalysis of islets cultured with DPS showed that the insulin stimulation index tended to be lower with the higher number of DPS, although differences did not reach statistical significance (100 islets + 75 DPS: 4.31 ± 0.55; 100 islets + 200 DPS: 3.72 ± 0.47; p = 0.25; n = 6). β-cell apoptosis Ductal cells had no detectable effect on β-cell apoptosis.

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