Barely Significant
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A paternal effect of MTHFR SNPs on gametes and embryos should not be overlooked: case reports.

J Assist Reprod Genet · 2019 · PMC6642231 · PMID 31119439

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a strong trendno p-value reported
In men, a strong trend in the relationship between MTHFR SNPs and fertility has been demonstrated [ 7 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.