Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies.

Dis Markers · 2019 · PMC6642763 · PMID 31360262

Europe PMC DOI

hedged sentences

0.0650

closest p · 1.3× alpha

0.1100

boldest claim

The sentences

borderline significantp = 0.065so close (0.05 < p ≤ 0.1)

In addition, a borderline significant moderate correlation between age and TCRB repertoire diversity was also found in all bDMARD-treated RA patients ( r = −0.68, p = 0.065) ( Figure S3C ).

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showed a trendp = 0.11not close (p > 0.1)

Our results revealed that the reduction of TCRB repertoire diversity showed a trend toward increased DAS28 ( r = −0.61, p = 0.11), CDAI ( r = −0.32, p = 0.44), and SDAI ( r = −0.32, p = 0.44) in all bDMARD-treated RA patients ( Figure 5(a) ).

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