Simvastatin pretreatment ameliorates t-PA-induced hemorrhage transformation and MMP-9/TIMP-1 imbalance in thromboembolic cerebral ischemic rats.

Neuropsychiatr Dis Treat · 2019 · PMC6643059 · PMID 31410004

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did not reach statistical significanceno p-value reported

In contrast, TIMP-1 expression increased after ischemic stroke; however, the difference between the SIM-/t-PA+ group and SIM+/t-PA+ group did not reach statistical significance ( Figure 2A – C ).

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