Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces <i>in vitro</i> HIV-1 Infection.

Results showed that even in the absence of CD8 + T cells, rhERAP2 addition to cell cultures resulted in a partial reduction of p24 levels in both HomoA and HomoB subjects (percentage of reduction compared to cells cultured without rhERAP2: HomoA 21%, HomoB 23%), however, these differences did not reach statistical significance ( Figure 2C ).

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