Although there was a slight trend towards a higher oral apparent clearance normalized to body surface area in Asian patients (median [range] 89.4 [25–250] l/h/m 2 ) compared with European patients (median [range] 76.7 [26–235] l/h/m 2 ), this trend did not reach statistical significance ( p = 0.07; Fig. 1 a).
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Effect of ethnicity on vinorelbine pharmacokinetics: a population pharmacokinetics analysis.
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