While LTP tended to be reduced in 12 month HETs, this result did not quite reach statistical significance ( Figures 3G,I , WT n = 8, heterozygous n = 7, unpaired t -test, p = 0.076).
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The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease.
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0.0760
0.0760
The sentences
While our data trended towards a lower paired-pulse ratio for shorter intervals at 6–9 months (homozygous) and 12 months (heterozygous), the data did not reach statistical significance.