Metformin reverses mesenchymal phenotype of primary breast cancer cells through STAT3/NF-κB pathways.

MBCDF and MBCD17 cells treated with MTF or with both IL-6 plus MTF showed a trend towards less proliferation than control cells, suggesting an inhibitory effect of MTF on IL-6-induced cell proliferation (Fig. 6 a, Additional file 3 ).

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