High IDO1 Expression Is Associated with Poor Outcome in Patients with Anal Cancer Treated with Definitive Chemoradiotherapy.

Oncologist · 2019 · PMC6656510 · PMID 30755500

Europe PMC DOI

hedged sentences

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closest p · 1.2× alpha

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boldest claim

The sentences

showed a trendp = .060so close (0.05 < p ≤ 0.1)

T1–T2) disease was specifically associated with a significantly increased risk of any recurrence or LRR (hazard ratio [HR] 3.41, p = .036 and HR 5.56, p = .029, respectively) and showed a trend for association with worse OS (HR 2.58, p = .060).

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a trend toward significanceno p-value reported

The association between IDO1 levels and clinical outcomes remained significant in a multivariate model that included all clinical parameters that either were significant or showed a trend toward significance on univariate examination (Table 3 ).

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