Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts.

PLoS Biol · 2019 · PMC6657915 · PMID 31306410

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Consistent with the increased number of memory OT-1 T cells, the d 3 response to a secondary immunization in a distant site with a low dose of 5-μg OVA showed a trend towards an increased OT-1 T-cell number in the draining LNs of iNOS −/− relative to WT mice ( S3H Fig ).

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