Antibody responses to flagellin C and Streptococcus gallolyticus pilus proteins in colorectal cancer.

Sci Rep · 2019 · PMC6659640 · PMID 31350458

Europe PMC DOI

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a positive trendno p-value reported

In the replication study MCC-Spain, the OR for CRC did not show a positive trend, although the highest risk was found in the highest FliC quartile (Q4 vs Q1, OR: 1.14, 95% CI: 0.81–1.59).

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a significant trendno p-value reported

We found a significant trend for higher antibody responses to FliC in CRC cases compared to controls in the Nijmegen/Detroit study, which could not be reproduced in the replication study MCC-Spain.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.