By PCA, there was nearly complete separation of groups at baseline, with a slight trend towards overlap at month-2 and month-6, culminating in near complete merger of values for the two groups at month-18, albeit with some outliers among TBDM participants.
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Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity.
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Sputum smear grade differences between TBDM and TB were highly significant when the combined participants from both countries were considered ( Figure 1b ).
Trends for higher likelihood of self-reported current or past smoking in the normoglycemic TB group did not reach statistical significance.
While there was some variation in the levels of specific analytes across the cohorts, an overall trend for declining levels of pro-inflammatory mediators and increasing levels of pro-resolving mediators was observed in the TBDM and TB groups alike.