Four variants (in EP300 , GATAD2A , KDM3B , and RERE ) showed nominally significant association with one or several cognitive task, while the risk allele for GATAD2A associated also with lower “Full Scale IQ.” Collectively, this study indicates that genetic variation in the NuRD core subunit GATAD2A or in the NuRD-interacting regulators CTIP2 and SATB2 contributes to cognitive impairment in SCZ.
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Chromatin Remodeling Complex NuRD in Neurodevelopment and Neurodevelopmental Disorders.
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