The following three GO terms, GO: 0090304 (nucleic acid metabolic process), GO: 0006139 (nucleobase-containing compound metabolic process), and GO: 0071704 (organic substance metabolic process), may also contribute to PPIs, considering that the nucleus region has been discussed to be quite significant for PPIs [ 56 – 58 ] and proteins turn out to be one of the major subgroups of organic substance in eukaryotic cells; these three GO terms may also actually contribute to the identification of PPIs.
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Analysis of Protein-Protein Functional Associations by Using Gene Ontology and KEGG Pathway.
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