Comparison between liver transplantation and resection for hilar cholangiocarcinoma: A systematic review and meta-analysis.

: 0.99, 95% CI: 0.73 to 1.34, p = 0.95; I 2 : 0%, p = 0.8].[ 26 , 27 , 29 ] However, there was a higher rate of tumors categorized as Bismuth-Corlette IV in the transplantation group than in the resection group [transplantation: 64/84 (76.2%), resection: 82/282 (29.1%)], even though this difference did not reach statistical significance (RR: 1.46, 95% CI: 0.73 to 2.94, p = 0.28; I 2 : 78%, p = 0.01).[ 27 – 29 ] Similarly, the differences noticed regarding the rates of involved lymph nodes between the two groups were comparable [transplantation: 15/124 (12.1%), resection: 127/364 (34.9%), RR: 0.43, 95% CI: 0.14 to 1.36, p = 0.15], but again with great heterogeneity among studies (I 2 : 81%, p = 0.006).[ 26 – 30 ].

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