Barely Significant
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Even a low dose of tamoxifen profoundly induces adipose tissue browning in female mice.

Int J Obes (Lond) · 2020 · PMC6669124 · PMID 30705393

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Tamoxifen induced a 24.8% increase in the serum insulin level of female mice but did not reach statistical significance ( Fig. 1D ).

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