In particular, one case-control study on 36 hypogonadal men, comprising 29 men with Hypo-H (20 with known cause and 9 idiopathic), and 7 men with Hyper-H, aged 22–68 years (median age 53 years), highlighted that TRT with 100 mg intramuscular testosterone enanthate once per week for 18 months significantly decreased total body and subcutaneous fat mass, whereas VAT was reduced but change did not reach statistical significance, as assessed at quantitative computed tomography ( 89 ).
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