Association of <i>Nrf2</i>, <i>SOD2</i> and <i>GPX1</i> Polymorphisms with Biomarkers of Oxidative Distress and Survival in End-Stage Renal Disease Patients.

Genome-wide association studies (GWAS) identified several genetic loci with highly significant associations with CKD [ 1 ].

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Regarding the byproducts of protein oxidative damage, we showed statistically significant differences only in terms of thiol groups, although other investigated biomarkers of protein oxidative damage showed a trend towards an increase in low-activity, Val , homozygotes.

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