We did, however, identify two notable trends which did not reach statistical significance: an elevated rate of Trp53 mutations in the claudin-low-like cluster (50% vs. 11%, p = 0.13, two-tailed Fisher’s exact test) and an elevated rate of Zfhx3 mutations also in the claudin-low-like cluster (37.5% vs. 0%, p = 0.08, two-tailed Fisher’s exact test).
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Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers.
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